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The observatory’s Rami Abdel Rahman said: “The Russian air strike hit a field clinic in the town of Sarmin, including a physiotherapist, a guard and a civil defence member.”
Sarmin lies in the northwestern province of Idlib, which has been regularly targeted by Russia’s military since the beginning of its air war in Syria on September 30.
The clinic was run by the Syrian-American medical society, whose staff confirmed that strikes had “severely damaged” the facility.
Russia’s defence ministry said on Wednesday that its armed forces had targeted Sarmin, but did not mention the hospital.
Russia has conducted more than 500 strikes against what it says are Islamic State group fighters.
But Moscow has come under fire for targeting non-extremist groups and inflicting civilian casualties.
The Observatory said on Tuesday that at least 127 of the 370 killed so far in Russia’s aerial war were civilians.
